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Facilities Yoyodyne Propulsion Systems worked out of included 40 Eridani A Starfleet Construction Yards, Copernicus Ship Yards and San Francisco Fleet Yards. Offices were also located throughout the Federation, including an office on Deep Space 9's Promenade. (Star Trek: The Next Generation; Star Trek: Deep Space Nine)
Some Starfleet starships Yoyodyne were involved in constructing included the:
- USS Brattain (TNG: "Night Terrors")
- USS Hathaway (TNG: "Peak Performance")
- USS Phoenix (TNG: "The Wounded")
- USS Sutherland (TNG: "Redemption II")
In 2411 Jasmine Velasquez blamed Yoyodyne incompetence on a series of failures on the newly launched USS Black Prince, ultimately including a failure of Alpha Section's warp core during contact with a Jem'Hadar attack ship squadron. (The War of the Masters: "A Good Compromise")