A Wthaure battle cruiser was a large Wthaure starship, equivalent in size and firepower to an Excelsior-class starship.

In 2369, Captain Noah Wrightson and the crew aboard the USS Cantabrian had a tense stand-off with a Wthaure battle cruiser when a subspace weapon exploded, heavily damaging the Cantabrian and nearly crippling the Wthaure battle cruiser. Despite an offer for help from the Cantabrian, the battle cruiser limped away. (Star Trek: The Cantabrian Expeditions: "Catalyst, Part One", "Catalyst, Part Two")

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