- Southern Cross
- could refer to:
- USS Southern Cross (NCC-1376), an Archon-class cruiser
- USS Southern Cross (NCC-1886), an Avenger-class heavy frigate
- USS Southern Cross (NCC-63550), an Akira-class battle cruiser
- Disambiguation page: If you followed a link to Southern Cross that brought you here, you might want to go back and change it to link to a more specific title. (For example: Southern Cross (some other term), or choose from one of those listed above.)