USS Shenandoah (NCC-571) was a destroyer on active duty in Starfleet during the mid-23rd century. (Orion Press)
Shenandoah was under the command of Commander James T. Kirk in 2264. Hikaru Sulu also served aboard Shenandoah, as its astrophysicist. Paul Giotto, later Enterprise security chief, was a guard on Shenandoah. (Orion Press: "The Spider's Lair")
By the 2290s, both Peter Kirk and Marcella DiFalco were assigned to Shenandoah. (Orion Press: "Return to Xantharus")