The USS Niagara (NCC-74461) was a Prometheus-class Federation starship in service with the Starfleet Third Fleet during the 24th century, under the command of Captain Edwin Sutton. (Star Trek: Pioneer)

Between 2374 and 2379, Chase Braga served aboard the Niagara as the Deputy Chief Medical Officer. In 2379, the Niagara transported him to the USS Pioneer for his transfer to the later ship as its Chief Medical Officer. ("The Removal, Part 1")

In 2378, the Niagara assisted the USS Pioneer in the rescue of President Ba'l from Ka'al. ("The Removal, Part 1")

In 2380, Captain Sutton was one of the captains recalled to Earth to select a new Starfleet Commander. ("The Teacher")

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