The USS Milburn (NCC-1901-B) was an Galaxy-class exploration cruiser in service with the Starfleet Third Fleet during the 24th century, under the command of Captain Kenneth William. (Star Trek: Pioneer)

The ship was named after the USS Milburn (NCC-1901), the ship commanded by Captain Donald Blaine.

In 2381, the Milburn spotted Tyson Calok around the Trajan Nebula. ("Almost Paradise")