The USS McCaffrey (NCC-63956) was an Akira-class starship in the late 24th century.

In 2374, the McCaffrey was assigned to be part of the Starfleet task force assigned to the Pilmarian-Steranmio area of space. (Star Trek: The Cantabrian Expeditions: "Said I Was Saved but You Never Said What From")

Named for the science-fiction author, Anne McCaffrey.

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