USS Kyushu (NCC-65491) was a New Orleans-class frigate on active duty in Starfleet during the 24th century.
In 2364, it was commanded by Captain Daniel. (Star Trek: Phoenix-X: "Remnants")
In 2367, it was destroyed at the Battle of Wolf 359 with 38 other Starfleet starships. (TNG: "The Best of Both Worlds, Part II")
The USS Prospect's sensors detected several escape pods and survivors from the Kyushu during the rescue effort at Wolf 359. (Star Trek: The Prospect Chronicles: "The Burnt Child")
The ship was named after Kyushu, the third-largest and most southwesterly island of the nation-state of Japan on Earth.