USS Horizon (NCC-1000-A) was a Constitution-class heavy cruiser on active duty in Starfleet during at least the late 2280s and early 2290s.

Horizon-A's commanding officer ca. 2290 was Captain James B. Herring. The ship was deployed to the Starfleet Twelfth Fleet at the time. (Starfleet International: USS Horizon-A)