The USS Horizon (NCC-1000) was a Federation Horizon-class cruiser starship in service to Starfleet in the late 22nd and early 23rd centuries.

The Horizon was laid down at UESPA, Starfleet Division, San Francisco Fleet Yards, Earth on 06 June 2190. She was eventually launched on the 14 May 2193, and commissioned on 10 October of that same year. (Heavy Cruiser Evolution Blueprints)

By 2197 the Horizon, under the command of Captain Stuart Mann, had encountered twelve civilizations including the Davitos and the Alpha Cruci. (Star Trek Spaceflight Chronology)