The USS Cole (NCC-89204) was an Olympic-class hospital ship in service during the late 24th century. As of 2385, Commander Stu Karsten was her commanding officer. (Henglaar, M.D.)
- Named after Rear Admiral Jennifer Cole, who died in 2383 from severe radiation poisoning after a Tholian attack in Star Trek: Hidden Frontier episode, "Hearts and Minds".
In an emergency, the Cole was equipped to treat over a thousand patients. (Henglaar, M.D.: "Final Exam")
Officers' quarters were located on deck 5, where visitors were not allowed to go. There was a lounge on deck 7 that was accessible to everyone aboard. (Henglaar, M.D.: "Final Exam")