The USS Cibola (NCC-69103) was a Federation El Dorado-class starship that saw service during the 24th century. The vessel was under the command of Captain Jessica Murrow.

The Cibola was the lead vessel for the 523rd Tactical Wing during the early months of the Dominion War. In mid-2374, while on patrol in Svandroth the 523rd was ambushed by Jem'Hadar forces and the Cibolo was destroyed when a torpedo struck its engineering hull causing the ship's warp core to explode. (The Dominion War Sourcebook: The Fires of Armageddon)

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