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Participating in the blockade of the Klingon-Romulan border during the Klingon Civil War in early 2368, the Charleston was near the USS Tian An Men, USS Hornet and USS Merrimac. (TNG: "Redemption II")
By 2378, the Charleston was a part of the Starfleet Third Fleet, under the command of Admiral Christopher Truman. In 2382, the Charleston participated in the Battle of Minark. (Star Trek: Pioneer, "Torment and Woe")
- USS Charleston article at Memory Alpha, the canon Star Trek wiki.
- USS Charleston article at Memory Beta, the non-canon Star Trek wiki.