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The tribble was an animal native to Iota Geminorum IV. Known for their prodigious reproductive rate, these round, furry creatures emitted cooing sounds while touched, which had a tranquilizing effect on the Human nervous system. Born pregnant, with sufficient food a single tribble could quickly increase its number exponentially through presumably asexual reproduction, bearing an average litter of ten every twelve hours. (TOS: "The Trouble with Tribbles")
Cardassians and Romulans were known to eat tribble stew. The Cardassians were said to make the best tribble meals in the galaxy. Also, since there isn't much meat in a tribble, either species can eat as many as six tribbles in a single meal. Also, Hydrans struck a deal with the Romulans to have the Romulans supply cooked tribbles to them. (RIS Bouteina)
In 2386, Doctor Lox genetically altered a tribble with the Klingon augment virus using a Genitronic replicator, causing the tribble to become sentient. The tribble multiplied and attempted to take over the USS Phoenix-X but were ultimately forced off to escape via the hijacked IKS Korinar. (Star Trek: Phoenix-X: "Triple Tribble Sunday)