Starbase Expanse 7 is a Federation deep space station located on the edge of the Typhon Expanse.

In 2372, the USS Cantabrian was directed to Starbase Expanse 7 to drop off non-Lelari civilians deported off Lelar Prime. The crew diverted to Caldea IV, responding to a distress call, before proceeding to SE7 to drop off the civilians. (Star Trek: The Cantabrian Expeditions: "Breaking Benjamin", "Isolation", "Two Hit, One Stone")

The Cantabrian also underwent minor repairs at SE7 before departing, under urgent orders, to investigate claims of survivors of the Myhr'an attacks weeks earlier. (Star Trek: The Cantabrian Expeditions: "Two Hit, One Stone")

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