South Africa is an African nation-state on Earth, part of the African Confederation. Pretoria is the executive capital city. People or things originating from South Africa are described as South African.
In 1968, ground stations in South Africa and Bermuda detected the US launch of an orbital nuclear warhead platform. (TOS: "Assignment: Earth")
Nelson Mandela was president during the 1990s.
The New Azania colony was founded by light-skinned refugees from South Africa and other African countries in the 21st century. (Star Trek: Avenger: "Belonging", Star Trek: Shadowstar Station: "A Separate War")
Dr. M'Benga, assistant chief medical officer of the USS Enterprise in the 2260s, was raised in Durban. (Orion Press: "The Hyperion Crew")
Lieutenant Russel Roose of the USS Excelsior was a native of Mandelaport in South Africa. (TOS novel: The Fearful Summons)
- In Enterprise: The First Adventure, Nyota Uhura attended a harp festival in Mandela City in 2264. It is assumed to be in South Africa, but is not directly stated to be so.
Alexandra de Groot was born near Pretoria, South Africa in 2327. (Star Trek: Shabonee)
Luther Sloan of Starfleet Intelligence -- and, later, Section 31 -- was also born in South Africa. (The Lost Era novel: Catalyst of Sorrows)
Petty Officer Second Class Juno Ichigaki of the USS Bajor was a South African of Japanese descent. (Bait and Switch: "Downbelow")
Lieutenant Commander Lucinda van der Merwe was born and raised in Cape Town. (The War of the Masters: "Academy Daze")