Sharon DeLonghi was a Starfleet officer in the Federation science corps. DeLonghi was a biologist aboard the science vessel USS Grissom (NCC-638). (Star Trek: Grissom)

DeLonghi was born in Italy to an Italian father and Greek mother.

Aboard the Grissom, she shared a bunkroom with Specialist Aabin, whom she considered a good friend. (Star Trek: Grissom)

DeLonghi and the Grissom crew were killed in 2285 when the Grissom was destroyed in orbit of the Genesis planet during a surprise attack by a Klingon Bird-of-Prey commanded by Commander Kruge. (Star Trek III: The Search for Spock)