Rigelian fever is a disease with the common symptom of a fever. Rigelian fever originated from the Rigel system.
Ualla Thall and the starship she was serving on visited Vulcan to treat an outbreak of Rigelian Fever. (Star Trek: The Cantabrian Expeditions)
Ryetalyn, a rare mineral, remains the only known cure. (TOS: "Requiem for Methuselah")
There were no known cases of Rigelian fever between 2339 and 2360. (TLE novel: Catalyst of Sorrows)