One Hundred Years of Solitude is a novel written by Gabriel García Márquez, published in Spanish in 1967 and English in 1970.

Considered Márquez's masterpiece, One Hundred Years of Solitude metaphorically covers the history of Colombia or Latin America with its mix of history, magical realism and fiction.

Cantabrian counselor Daniel Radke was reading One Hundred Years of Solitude when Cantabrian commanding officer Noah Wrightson fell ill with CACS in 2372; he claimed he'd read the book "at least a dozen times". Radke also felt Wrightson, an avid classical English literature fan, would not like it. (Star Trek: The Cantabrian Expeditions: "Isolation")

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