Odysseus-class starships were an experimental class of Starfleet vessels in service from approximately 2280-2344.

The most distinct feature of the Odysseus-class starships were their sleeker hull design and thin nacelles. It was theorized at the time of construction that the engine nacelle design would allow for more efficient warp field generation. Though the Odysseus-class ships were functional, the nacelles never provided any significant advantage.

The USS Lexington-A was an Odysseus-class starship launched in 2286. (The Lexington Adventures)

Only eight Odysseus-class vessels were constructed, and by 2311 only two were still in service, one of them the USS Agamemnon. (Star Trek: The Lost Era novel: Serpents Among the Ruins)

In the 2350s, another Odysseus class vessel, the USS Ajax, was among several starships the Federation sold to Magna Roma to become part of their planetary defense force. (Star Trek: Pendragon)

In 2374 at the height of the Dominion War, the USS Kamcaira was released from the Starfleet Orbital Museum and served as part of an emergency defense fleet to protect Earth from further attacks. At the conclusion of the war the ship was re-retired and returned to her Museum berth.

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