Nathan Hale was a hero of Earth's American Revolution. He was immortalized by his famous quote "My only regret is that I have but one life to lose for my country."
When the USS Voyager was controlled by the Kazon, leaving only the Doctor and Lon Suder to recapture the ship, the doctor told himself that he was no Che Guevara or Nathan Hale and that he was "a doctor and not a revolutionary". (VOY: "Basics, Part II")
Hale's famous quote was the ship's motto of the USS Gustav P. Remington on the vessel's dedication plaque. (Star Trek: Remington)