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Despite the economic downturns of the first quarter of the 21st century, several nation-states devoted a portion of their respective GDPs towards the construction of generation ships that would help some of their populations colonize the exoplanets discovered by Earth's space-based telescopes and unmanned probes. The impetus to build these generation ships was exacerbated by the near-destruction of Earth by asteroids that were fortunately diverted. (TLE novel: The Sundered)
In the late 2040s, one such generation ship -- the Canaan -- was launched towards a binary system (with one of the components a G-type star) 50 light-years from Earth, in the constellation of Ophiuchus. Most of those aboard in biostasis were from the United States of America, the European Union, Russia and Israel; they sought to escape a world in the nascent stages of World War III.
Canaan arrived at its destination c. 2096. In the intervening years on Earth, much of the Middle East had been devastated by the events of 1 May 2053, though nanotechnological repairs made with the help of the Vulcans were scrubbing the region of radiation damage. The post-Eugenics Wars United Nations resolution of 1998 -- proscribing certain lines of genetic research and methodology -- was put in abeyance so that any genetic damage of survivors and their descendants could be repaired.
At least one warp-driven generation ship, the Yosef, was launched as a follow-up mission in the early 22nd century. Once the existence and establishment of Hebron was confirmed, several colonization missions were launched, starting in the 2150s.
Hebron, in Israel, is one of the four holiest cities of Judaism.