The Enterprise (II) subclass of Constitution-class heavy cruisers debuted in 2286. (Star Trek IV: The Voyage Home, Ships of the Star Fleet, vol. 1 [revised])

The following four starships of this class were refitsUSS Excalibur, USS Exeter, USS Farragut and USS Lexington. A fifth, USS Enterprise-A, was refit from another Constitution-class heavy cruiser and was a successor to the destroyed USS Enterprise.

There were at least seven new-build starships of this class, including: USS Alliance, USS America, USS Levant, USS Raritan, USS Scipion, USS Temeraire and USS Ticonderoga.

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