A disruptor pistol was a type of directed-energy weapon used by the Klingons, Romulans and Breen as handguns. (Star Trek Generations)

Disruptor pistols were used to kill were-hawks in order to rescue a stranded Hydran away team. (RIS Bouteina: "Night of the Were-Hawks")

Lyrans engaged in pistol duels, much like Far West gunslingers. Akril, the security chief of the Enterprise (BC-348) fought the first officer of Starbase 148 in a disruptor pistol duel, and prevailed. (Star Trek: The Stoneship Files: "Attack on the Laboratory")

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