Children's Enclaves were orphanages run by the Federation Children's Administration. Such institutions were located in many areas of Federation space. Several of these facilities located on Earth and its colonies date from the early 22nd century (or earlier), and fell under the Children's Administration's jurisdiction after 2161.
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- Enclave J-12 in Christopher's Landing, Titan was specifically charged with caring for the orphaned children of deceased Starfleet officers. Timothy Sinclair and Jay Allan were raised there, as was Cody Sinclair. (Star Trek: Pendragon)
- Lee Kelso was raised in the Los Angeles Children's Enclave. (TOS novel: Constitution; Star Trek: Pendragon)
- Yuri Butler was raised in the Childen's Enclave of Moscow. (Star Trek: Pendragon)