A biosynthetic limb is a prosthetic limb made for patients who had lost limbs through injury or disease.

Nog received a biosynthetic leg after losing his leg during the Siege of AR-558. (DS9: "The Siege of AR-558")

Test pilot Samantha Beckett suffers a terrible accident in 2369, resulting in almost 50% of her body to be replaced with biosynthetic components, including both legs, right arm, and several organs. (Star Trek: Banshee Squadron)

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