|2162 2163 2164 2165 2166 2167 2168|
|2130s 2140s 2150s 2160s 2170s 2180s 2190s|
|21st century - 22nd century - 23rd century|
- Starfleet retires the NX-04 Discovery, formally ending the service of the NX class ships. (Star Trek: Discovery)
- January 1 - paternity leave for Malcolm Reed formally ends (In Between Days: Fortune).
- March - Record for inbound travel from Port Cochrane, Alpha Centauri to Earth is broken by Bison-class SS Pacific Princess: 47 days, 20 hours, 7 minutes (11.1 days per light-year). However, the ship's reactor had been severely damaged by running at 97 percent maximal capacity; Pacific Princess was retired from service later in the year. (The Starfleet Museum: Bison-Class Transports)
- April 19 - the USS Cochrane and the Columbia (NX-02) travel to Daranaea on a mission of scientific interest (In Between Days: Take Back the Night).
- May 8 - Leonora Digiorno gets her doctorate, in English (In Between Days: Fortune).
- May 8 - Leonora Digiorno (mirror), an abuse victim, is murdered by her lesbian lover, the alcoholic Leah Benson (mirror), in an argument over purchasing more Alcohol for Benson (In Between Days: Fortune).
- November 5 - Daranaean child Inta steals cookies and stuffs them into her pouch, thereby revealing that she can walk upright (In Between Days: Temptation).
- December 20 - holiday gifts are exchanged between the wealthy Daranaean family of Vidam, Dratha, Trinning and others, and the USS Cochrane (In Between Days: Some Assembly Required).
- Daedalus-class USS Lincoln destroyed by a warp core breach. (The Starfleet Museum: Museum Timeline)
- marriage of Karin Bernstein and Ethan Shapiro (In Between Days: Fortune).
- July 11 - Calafan Yinora is born, to Yimar (In Between Days: Fortune).
- November - Ines Ramirez is born, to Jennifer Crossman and Francisco Ramirez (In Between Days: Fortune).