|2157 2158 2159 2160 2161 2162 2163|
|2130s 2140s 2150s 2160s 2170s 2180s 2190s|
|21st century - 22nd century - 23rd century|
- February - The USS Columbia (NX-02) makes First contact with a species called Daranaeans, which are sentient marsupial canids (In Between Days: The Cure is Worse Than the Disease).
- April 9 - Charles Tucker III (mirror) and Elizabeth Cutler (mirror), along with their son, Charles Tucker IV, become citizens of the Lafa System (In Between Days: Ceremonial).
- April 25 - Chandler Masterson reveals to Deborah Haddon how he came to be in possession of Charles Tucker III's stuffed hamster, Stella (In Between Days: Where No Gerbil Has Gone Before).
- May 5 - Lili O'Day, Douglas Jay Hayes Beckett, Joss Beckett and Marie Patrice Beckett arrive on Ceres for the birth of Thomas Digiorno-Madden (In Between Days: Tumult).
- May - A squadron of Romulan sublight fightercraft penetrates the defenses of the Sol system, and attacks Mars and Earth. Nuclear warheads from two of the fighters destroy Madrid and Tunis. (ENT novel: The Romulan War: To Brave the Storm)
- August 4 - Laura Hayes, sister of J. Hayes, is a part of negotiating peace with the Romulan Star Empire (In Between Days: Achieving Peace).
- August 15 - Ruby Brannagh is sexually assaulted and left for dead (In Between Days: Shell Shock).
- August 16 - Several members of Starfleet are detained in connection with the investigation into the attack on Ruby Brannagh, including Malcolm Reed, Daniel Chang, and Brooks Haynem. Malcolm meets with his assigned attorney, Dash Nolan (In Between Days: Shell Shock).
- August 17 - Attorney Dash Nolan, subpoena in hand, opens up Malcolm Reed's quarters on the Enterprise in order to search for evidence. Jefferson Davis Paxton is apprehended, and vows allegiance to Terra Prime (In Between Days: Shell Shock).
- August 29 - Ruby Brannagh awakens from a coma (In Between Days: Shell Shock).
- September 21 - Jefferson Davis Paxton confesses to assaulting and raping Ruby Brannagh, claiming he perpetrated the crime to try to frame Starfleet, blaming them for his father, John Frederick Paxton's death in prison (In Between Days: Shell Shock).
- 'November - First contact with a species called the Arisians, who have no women, results in some of Hoshi Sato's female hormones being stolen from her body in order for the Arisians to make women. In exchange, she and her bodyguard, MACO Franklin Thomas Todd, are injected with a substance that makes Hoshi irresistible (In Between Days: There's Something About Hoshi).
- The Battle of Cheron took place, and ended the Earth-Romulan War in Earth's favor. (ENT: "In a Mirror, Darkly, Part II", ENT novel: The Romulan War: To Brave the Storm)
- January 11 - Marie Patrice Beckett is born to Douglas Jay Hayes Beckett and Lili O'Day (In Between Days: Temper).
- May 6 - Thomas Digiorno-Madden is born to Douglas Jay Hayes Beckett and Melissa Madden (In Between Days: Tumult).
- June 1 - Takara Sato and Takeo Sato are born to Hoshi Sato (mirror) and Chandler Masterson (mirror) (In Between Days: Temper).