|2154 2155 2156 2157 2158 2159 2160|
|2120s 2130s 2140s 2150s 2160s 2170s 2180s|
|21st century - 22nd century - 23rd century|
- January - Andrew Miller and Karin Bernstein go on their third date as Ethan Shapiro, Azar Hamidi and Maryam Haroun observe (In Between Days: Waiting).
- May 11 - Melissa Madden and Leonora Digiorno meet for the first time, on Ceres (In Between Days: Fortune).
- May 12 - As part of the cover story allowing Jun Sato to live, Empress Hoshi Sato is told that Richard Daniels died on this day when his ship crashed on Daranaea (Times of the HG Wells: You Mixed-Up Siciliano).
- May - Leonora Digiorno informs her family that she has fallen in love (In Between Days: An Announcement).
- June - Vulcans are captured by Witannen and made a part of a captive breeding program (In Between Days: Together).
- September - The Battle of Hell's Gate during the Earth-Romulan War. (The Starfleet Museum: The Development of Matter-Antimatter Drives, Farragut-Class Fleet Monitors)
- October 28 - Lili O'Day and Douglas Jay Hayes Beckett make contact for the first time (In Between Days: Reversal).
- October 30 - Shelby Pike offers Travis Mayweather an apple as a prelude to flirting (In Between Days: Apple).
- November 13 - Douglas Jay Hayes Beckett crosses over from the Mirror universe to the prime universe (In Between Days: Reversal).
- November 15 - Douglas Jay Hayes Beckett proposes Marriage to Lili O'Day (In Between Days: Reversal).
- November 16 - Lili O'Day and Douglas Jay Hayes Beckett arrive on Lafa II to begin retirement (In Between Days: Local Flavor).
- November - Erell, an Andorian, is born to Leveqa and Serin, and is smothered by her own parents, who are in a Witannen captive breeding program (In Between Days: Together).
- Commander Charles Clow dies aboard Discovery. (Star Trek: Poseidon - The Birth of the Federation)
- November 10 - High Priestess Yipran (mirror) is murdered by a political faction on Lafa II (In Between Days: Reversal).
- November 13 - Deborah Haddon (mirror) is killed by an explosion in the USS Defiant's Transporter room, intended as a diversion to cover the escape of Douglas Jay Hayes Beckett (In Between Days: Reversal).